Improving DNA Data Capacity:Forensic Parameters and Genetic Structure Analysis of Jinjiang Han Population with the MicroreaderTM Y Prime Plus ID System

• Published in: 当代医学科学（英文） Vol. 42; no. 2; pp. 462 - 466
• Main Authors: Lu-yao LI, De-qing WU, Li-lan YAO, Feng LI, Chao LIU, Fu-quan JIA
• Format: Journal Article
• Language: English
• Published: Department of Pathology,the First Affiliated Hospital of Xi'an Jiao tong University,Xi'an 710061,China%Forensic DNA laboratory of Jinjiang Public Security Bureau,Jinjiang 362200,China%Center of Forensic Expertise,Affiliated Hospital of Zunyi Medical University,Zunyi 563099,China%Hohhot Public Security Bureau,Hohhot 010000,China%Department of Forensic Medicine,Inner Mongolia Medical University,Hohhot 010059,China 2022
• Subjects: Jinjiang Han; forensic genetics; MicroreaderTM Y Prime Plus ID System; haplotype diversity; Y-short tandem repeat
• ISSN: 1672-0733
• DOI: 10.1007/s11596-022-2570-z

Objective:Population genetic analysis based on genetic markers harbors valuable forensic applications.In this regard,it is informative and imperative to explore Han groups as they are the largest population of China.In particular,there is a largely underrepresented amount of information from recent decades regarding the southeast costal Han Chinese.Therefore,the aim of this study is to investigate the available genetic characteristics of the Han population living in the Jinjiang,Fujian Province,Southeastern China.Methods:We sampled 858 saliva samples and used the commercially available MicroreaderTM Y Prime Plus ID System to identify population data of Y-short tandem repeat(STR)loci of this region.Results:A total of 822 different haplotypes were observed.The overall haplotype diversity,discriminatory power and haplotype match probability were 0.9999,0.9999 and 0.0012,respectively.Conclusion:Our results showed that the Jinjiang Han population was closely genetically related to Han groups of China.Overall,we identified a set of 37 Y-STRs that are highly polymorphic,and that can provide meaningful information in forensic practice and human genetic research.