Boric acid as a precatalyst for BH-catalyzed hydroboration
We report that boric acid, BO 3 H 3 , is a good precatalyst for the BH 3 -catalyzed hydroboration of esters using pinacolborane as a borylation agent. Using microwave irradiation as an energy source, we demonstrated that a dozen esters were converted into the corresponding boronate ethers in good yi...
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| Published in: | RSC advances Vol. 11; no. 51; pp. 31941 - 31949 |
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| Main Authors: | , , |
| Format: | Journal Article |
| Published: |
28-09-2021
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| Online Access: | Get full text |
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| Summary: | We report that boric acid, BO
3
H
3
, is a good precatalyst for the BH
3
-catalyzed hydroboration of esters using pinacolborane as a borylation agent. Using microwave irradiation as an energy source, we demonstrated that a dozen esters were converted into the corresponding boronate ethers in good yields. It was also possible to use boric acid as a precatalyst to reduce carbonates and alkynes. Considering the hazardous and pyrophoric nature of BH
3
solutions, boric acid proves to be a safe and green precatalyst for the metal-free reduction of unsaturated species.
Cheap and air-stable boric acid is shown to be a good precatalyst for BH
3
hydroboration of esters and carbonates. |
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| Bibliography: | 10.1039/d1ra05945a Electronic supplementary information (ESI) available. See DOI |
| ISSN: | 2046-2069 |
| DOI: | 10.1039/d1ra05945a |