Intensity of the peroxidation of membrane lipids and metabolism of lymphocytes in viral hepatitis patients

Patients with acute viral hepatitis B were found to have an increase in the processes of peroxidization of lymphocyte membrane lipids and in the activity of superoxide dismutase, an antioxidant enzyme, depending on the period of the disease and its severity. Patients with a severe form of the diseas...

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Bibliographic Details
Published in:	Žurnal mikrobiologii, ėpidemiologii i immunobiologii no. 5; p. 64
Main Authors:	Antonova, T V, Nikolaenko, S L
Format:	Journal Article
Language:	Russian
Published:	Russia (Federation) 01-09-1998
Subjects:	Acute Disease Adolescent Adult Hepatitis B - blood Hepatitis C - blood Humans Lipid Peroxidation - physiology Lymphocytes - metabolism Male Membrane Lipids - blood
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Summary:	Patients with acute viral hepatitis B were found to have an increase in the processes of peroxidization of lymphocyte membrane lipids and in the activity of superoxide dismutase, an antioxidant enzyme, depending on the period of the disease and its severity. Patients with a severe form of the disease were found to have specific features of the intracellular metabolism of lymphocytes in comparison with patients having moderate forms of the disease. To a lesser degree, the characteristics of lymphocytes in hepatitis cases depended of the etiology of the disease, caused by hepatitis virus B, C or the combination of both. The properties of lymphocytes were found to reflect the immune reactiveness of the body and could be used for evaluating the severity of the disease, prognostication and the achievement of convalescence.
ISSN:	0372-9311