Assessment of the severity of grave cranio-cerebral injury and its outcome according to the state of energy metabolism in the brain

Assessment of the severity of grave cranio-cerebral injury and its outcome according to the state of energy metabolism in the brain

A dynamic study of the arteriovenous oxygen and lactic acid content difference, as well as a study of the CSF content of the lactic acid in patients with a severe craniocerebral trauma permitted to evaluate the severity of the pathological process and the results of its treatment. A growing producti...

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Bibliographic Details
Published in:Voprosy neirokhirurgii no. 3; p. 37
Main Authors: Promyslov, M Sh, Vorob'ev, Iu V
Format: Journal Article
Language:Russian
Published: Russia (Federation) 01-05-1976
Subjects:
Brain - metabolism
Brain Injuries - blood
Brain Injuries - diagnosis
Brain Injuries - metabolism
Energy Metabolism
Humans
Lactates - blood
Lactates - cerebrospinal fluid
Oxygen Consumption
Prognosis
Skull - injuries
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Summary:A dynamic study of the arteriovenous oxygen and lactic acid content difference, as well as a study of the CSF content of the lactic acid in patients with a severe craniocerebral trauma permitted to evaluate the severity of the pathological process and the results of its treatment. A growing production of lactic acid by the brain and its progressive accumulation in the CSF to a high level as 45-50 mg%, and a sharp dissociation between the increasing lactate level in the CSF and its growing concentration in the venous blood flowing from the brain is a prognostic sign of an unfavourable course and outcome of the disease.