Necessity for immunologic studies in blood transfusion therapy

162 samples of blood from sensitized patients were investigated immunohematologically. All the patients were in need of blood transfusions. Immunization to HLA-antigens, to leukocyte and erythrocyte antigens was found in 74.0% and 25.4% of the patients, respectively. One patient (0.6%) had an extrem...

Full description

Saved in:

Bibliographic Details
Published in:	Gematologiia i transfuziologiia Vol. 39; no. 3; p. 14
Main Authors:	Nersisian, V M, Musaelian, N O, Martirosian, I G
Format:	Journal Article
Language:	Russian
Published:	Russia (Federation) 01-05-1994
Subjects:	Adolescent Blood Transfusion Female Humans Immunologic Tests Pregnancy
Online Access:	Get more information
Tags:	Add Tag No Tags, Be the first to tag this record!

Description
Summary:	162 samples of blood from sensitized patients were investigated immunohematologically. All the patients were in need of blood transfusions. Immunization to HLA-antigens, to leukocyte and erythrocyte antigens was found in 74.0% and 25.4% of the patients, respectively. One patient (0.6%) had an extremely rare immunization to antigens D and c of Rh-Hr system. Before hemotransfusion the blood from the donor, recipient and their relatives was subjected to typing by various antigens of the red cell (ABO, Rh-Hr, MNSs, P, Duffy, Kidd, Kell-Chellano) and leukocyte (HLA-A, HLA-B, HLA-C, HLA-DR) systems. Blood transfusions were performed after individual blood matching by compatibility to basic red cell antigens (A, B, O, D, C, E, c, M, N, K, Fya, Ika and to wide-spectrum antigens HLA according to Terasaki scale. The blood transfusions following immunological matching proceeded without adverse reactions making the treatment more effective.
ISSN:	0234-5730