Influence of variations of Ca++ on responses of segments of the isolated coronary artery to acetylcholine

The effect of external calcium concentration on the Ach-induced contraction of coronary arteries was studied in vitro. It resulted that the effect of Ach was enhanced by the increase, or reduced by the decrease of calcium concentration. It is concluded that, as it was known for the intestinal smooth...

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Bibliographic Details
Published in:	Bollettino della Societa italiana di biologia sperimentale Vol. 54; no. 17; p. 1647
Main Authors:	Bettini, V, Martino, R, Legrenzi, E, Vazzoler, C
Format:	Journal Article
Language:	Italian
Published:	Italy 15-09-1978
Subjects:	Acetylcholine - pharmacology Animals Calcium - pharmacology Cattle Coronary Vessels - drug effects Drug Interactions In Vitro Techniques
Online Access:	Get more information
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Summary:	The effect of external calcium concentration on the Ach-induced contraction of coronary arteries was studied in vitro. It resulted that the effect of Ach was enhanced by the increase, or reduced by the decrease of calcium concentration. It is concluded that, as it was known for the intestinal smooth muscle, also for the smooth muscle of the coronary arteries, the contractile effect of Ach is dependent on the calcium of the medium.
ISSN:	0037-8771