A Novel Multicellular Placental Barrier Model to Investigate the Effect of Maternal Aflatoxin B 1 Exposure on Fetal-Side Neural Stem Cells

Ingestion of food toxins such as aflatoxin B (AFB ) during pregnancy may impair fetal neurodevelopment. However, animal model results may not be accurate due to the species' differences, and testing on humans is ethically impermissible. Here, we developed an in vitro human maternal-fetal multic...

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Bibliographic Details

Published in:	Toxins Vol. 15; no. 5
Main Authors:	Zhou, Zhiwei, Luo, Dongmei, Li, Mengxue, Lao, Guangjie, Zhou, Zhiqiang, Dinnyés, András, Xu, Wenming, Sun, Qun
Format:	Journal Article
Language:	English
Published:	Switzerland 27-04-2023
Subjects:	Aflatoxin B1 - metabolism Aflatoxin B1 - toxicity Animals DNA Damage Female Humans Liver - metabolism Mycotoxins - metabolism Placenta - metabolism Pregnancy multicellular in vitro model neural stem cells DNA damage placental barrier
Online Access:	Get full text
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