Granular Cell Astrocytoma

Granular cell astrocytoma (GCA) is a rare glial neoplasm composed of abundant granular cytoplasm gives immunoreactivity for GFAP and S100 stains. We report a case of GCA in a 64 years old male presented with history of fits, right sided weakness and loss of consciousness. The microscopy showed sheet...

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Bibliographic Details
Published in:	Journal of Ayub Medical College, Abbottabad : JAMC Vol. 35; no. 1; p. 158
Main Authors:	Batool, Ayma, Bashir, Azra, Javeed, Saira, Zaman, Samina, Chughtai, Akhtar Sohail
Format:	Journal Article
Language:	English
Published:	Pakistan 01-02-2023
Subjects:	Astrocytoma - diagnostic imaging Coloring Agents Diagnosis, Differential Humans Male Microscopy Middle Aged Staining and Labeling Immunohistochemistry, GFAP Granular cell Astrocytoma
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Summary:	Granular cell astrocytoma (GCA) is a rare glial neoplasm composed of abundant granular cytoplasm gives immunoreactivity for GFAP and S100 stains. We report a case of GCA in a 64 years old male presented with history of fits, right sided weakness and loss of consciousness. The microscopy showed sheets of large cells with abundant eosinophilic granular cytoplasm. No high-grade features were seen. Its differential diagnosis includes most of the benign histiocytic conditions. Granular cell astrocytoma has an aggressive clinical course and its survival rate is less than 1 year. That's why early correct diagnosis is very essential.
ISSN:	1819-2718