Generalised, symmetric muscle weakness in survivors after intensive therapy

ICU-acquired weakness (ICUAW) is often found in critically ill patients and is characterised by a generalised, symmetric weakness, affecting limb (proximal more than distal) and respiratory muscles. It is a diagnosis of exclusion. ICUAW is associated with increased morbidity and mortality, and decre...

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Bibliographic Details
Published in:	Ugeskrift for læger Vol. 183; no. 41
Main Authors:	Nedergaard, Helene Korvenius, Estrup, Stine, Storgaard, Anders, Tankisi, Hatice
Format:	Journal Article
Language:	Danish
Published:	Denmark 11-10-2021
Subjects:	Critical Illness Humans Intensive Care Units Muscle Weakness - etiology Quality of Life Survivors
Online Access:	Get more information
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Summary:	ICU-acquired weakness (ICUAW) is often found in critically ill patients and is characterised by a generalised, symmetric weakness, affecting limb (proximal more than distal) and respiratory muscles. It is a diagnosis of exclusion. ICUAW is associated with increased morbidity and mortality, and decreased quality of life. The aetiology is not completely understood, and there is no established treatment or prevention yet. The most important risk factors are high disease severity, multiorgan failure, systemic inflammation and prolonged immobilisation. Individual needs for rehabilitation must be defined, as argued in this review.
ISSN:	1603-6824