Central Pattern Generators Reveal Neuronal Circuit Dynamics Across Many Timescales
Central pattern generators (CPGs) are neuronal circuits that can autonomously generate rhythmic behaviors such as breathing, locomotion and vocalization (Marder and Bucher 2001). The study of these circuits is important because they are essential for survival. However, their investigation has also b...
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| Published in: | Developmental neurobiology (Hoboken, N.J.) |
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| Main Authors: | , |
| Format: | Journal Article |
| Language: | English |
| Published: |
United States
20-04-2020
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| Online Access: | Get full text |
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| Summary: | Central pattern generators (CPGs) are neuronal circuits that can autonomously generate rhythmic behaviors such as breathing, locomotion and vocalization (Marder and Bucher 2001). The study of these circuits is important because they are essential for survival. However, their investigation has also been prioritized for pragmatic reasons: because they can produce naturalistic rhythmic patterns without sensory feedback, they often continue to function in a quasi-normal way in ex vivo preparations (Rhodes et al., 2007. Many CPGs, such as the stomatogastric ganglion (STG) circuit that controls crustacean stomach movements, represent some of the best understood neuronal circuits in all of neuroscience, and have provided fundamental insights into nervous system mechanisms such as neuromodulation, synaptic plasticity, and activity-dependent homeostasis (Daur, Nadim, and Bucher 2016). |
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| ISSN: | 1932-846X |