HER2-amplified cervical gastric-type mucinous carcinoma with a primitive enterocyte phenotype: A case report

Gastric-type mucinous carcinoma is a subtype of adenocarcinoma of the uterine cervix whose differentiation is characterized by cytoplasmic pyloric gland mucins. In the stomach, adenocarcinoma may occasionally show foetal gut differentiation. However, such retro-differentiation is rarely reported in...

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Published in:Histopathology
Main Authors: Fujimoto, Masakazu, Minamiguchi, Sachiko, Ishida, Ayami, Sumiyoshi, Shinji, Horikawa, Naoki, Chigusa, Yoshitsugu, Mandai, Masaki, Haga, Hironori
Format: Journal Article
Language:English
Published: England 18-04-2020
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Abstract Gastric-type mucinous carcinoma is a subtype of adenocarcinoma of the uterine cervix whose differentiation is characterized by cytoplasmic pyloric gland mucins. In the stomach, adenocarcinoma may occasionally show foetal gut differentiation. However, such retro-differentiation is rarely reported in cervical gastric-type mucinous carcinoma. Herein, we present a case of gastric-type mucinous carcinoma with a primitive enterocyte phenotype whose clear cell morphology mimicked clear cell carcinoma (CCC) in its preoperative biopsy.
AbstractList Gastric-type mucinous carcinoma is a subtype of adenocarcinoma of the uterine cervix whose differentiation is characterized by cytoplasmic pyloric gland mucins. In the stomach, adenocarcinoma may occasionally show foetal gut differentiation. However, such retro-differentiation is rarely reported in cervical gastric-type mucinous carcinoma. Herein, we present a case of gastric-type mucinous carcinoma with a primitive enterocyte phenotype whose clear cell morphology mimicked clear cell carcinoma (CCC) in its preoperative biopsy.
Author Ishida, Ayami
Horikawa, Naoki
Chigusa, Yoshitsugu
Minamiguchi, Sachiko
Haga, Hironori
Fujimoto, Masakazu
Mandai, Masaki
Sumiyoshi, Shinji
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  givenname: Masakazu
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  surname: Fujimoto
  fullname: Fujimoto, Masakazu
  organization: Department of Diagnostic Pathology, Kyoto University, Kyoto, Japan
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  givenname: Sachiko
  surname: Minamiguchi
  fullname: Minamiguchi, Sachiko
  organization: Department of Diagnostic Pathology, Kyoto University, Kyoto, Japan
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  givenname: Ayami
  surname: Ishida
  fullname: Ishida, Ayami
  organization: Department of Diagnostic Pathology, Kyoto University, Kyoto, Japan
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  surname: Sumiyoshi
  fullname: Sumiyoshi, Shinji
  organization: Department of Diagnostic Pathology, Kyoto University, Kyoto, Japan
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  givenname: Naoki
  surname: Horikawa
  fullname: Horikawa, Naoki
  organization: Department of Gynecology and Obstetrics, Kyoto University, Kyoto, Japan
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  givenname: Yoshitsugu
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  fullname: Chigusa, Yoshitsugu
  organization: Department of Gynecology and Obstetrics, Kyoto University, Kyoto, Japan
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  givenname: Masaki
  surname: Mandai
  fullname: Mandai, Masaki
  organization: Department of Gynecology and Obstetrics, Kyoto University, Kyoto, Japan
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  givenname: Hironori
  surname: Haga
  fullname: Haga, Hironori
  organization: Department of Diagnostic Pathology, Kyoto University, Kyoto, Japan
BackLink https://www.ncbi.nlm.nih.gov/pubmed/32304250$$D View this record in MEDLINE/PubMed
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Snippet Gastric-type mucinous carcinoma is a subtype of adenocarcinoma of the uterine cervix whose differentiation is characterized by cytoplasmic pyloric gland...
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Title HER2-amplified cervical gastric-type mucinous carcinoma with a primitive enterocyte phenotype: A case report
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