HER2-amplified cervical gastric-type mucinous carcinoma with a primitive enterocyte phenotype: A case report

HER2-amplified cervical gastric-type mucinous carcinoma with a primitive enterocyte phenotype: A case report

Gastric-type mucinous carcinoma is a subtype of adenocarcinoma of the uterine cervix whose differentiation is characterized by cytoplasmic pyloric gland mucins. In the stomach, adenocarcinoma may occasionally show foetal gut differentiation. However, such retro-differentiation is rarely reported in...

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Bibliographic Details
Published in:Histopathology
Main Authors: Fujimoto, Masakazu, Minamiguchi, Sachiko, Ishida, Ayami, Sumiyoshi, Shinji, Horikawa, Naoki, Chigusa, Yoshitsugu, Mandai, Masaki, Haga, Hironori
Format: Journal Article
Language:English
Published: England 18-04-2020
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Summary:Gastric-type mucinous carcinoma is a subtype of adenocarcinoma of the uterine cervix whose differentiation is characterized by cytoplasmic pyloric gland mucins. In the stomach, adenocarcinoma may occasionally show foetal gut differentiation. However, such retro-differentiation is rarely reported in cervical gastric-type mucinous carcinoma. Herein, we present a case of gastric-type mucinous carcinoma with a primitive enterocyte phenotype whose clear cell morphology mimicked clear cell carcinoma (CCC) in its preoperative biopsy.
ISSN:1365-2559