Burkitt's lymphoma nodular cystic hepatosplenic, in HIV patient. Case report

• Published in: Revista medica del Instituto Mexicano del Seguro Social Vol. 57; no. 3; p. 187
• Main Authors: De la Cruz-Hernández, Ibis, Mejía-Martínez, Juan Carlos, Soberanes-Cerino, Candelario de Jesús, Mejía-Picasso, Carlos Alberto
• Format: Journal Article
• Language: Spanish
• Published: Mexico 02-05-2019
• Subjects: Burkitt Lymphoma - diagnostic imaging; Burkitt Lymphoma - etiology; Burkitt Lymphoma - pathology; HIV Infections; Humans; Liver Neoplasms - diagnostic imaging; Liver Neoplasms - etiology; Liver Neoplasms - pathology; Lymphoma, AIDS-Related - diagnostic imaging; Lymphoma, AIDS-Related - etiology; Lymphoma, AIDS-Related - pathology; Male; Splenic Neoplasms - diagnostic imaging; Splenic Neoplasms - etiology; Splenic Neoplasms - pathology; Young Adult; HIV; Burkitt Lymphoma; Lymphoma, AIDS Related
• ISSN: 2448-5667

Patients with human immunodeficiency virus (HIV) are more likely to develop cancer. Malignant lymphomas are the main cancer group seen in these patients. Diffuse large B-cell lymphoma including central nervous system lymphoma and Burkitt's lymphoma account for 90% of HIV-related non-Hodgkin's lymphomas.
A 22-year-old man with fever up to 39 ° C, malaise, excessive tiredness and night sweats, loss of 8 kg of weight, abdominal pain in the right hypochondrium, all 5 months before hospitalization. Hemoglobin: 9.5 g/dL, leukocytes 5.13 x 103/mm3, platelets 124 000 cel/mm3; albumin 2.9 g/dL, alanine aminotransferase 28 IU/L, aspartate aminotransferase 105 IU/L; HIV reactive, beta 2 microglobulin: 20 000 ng/mL. Viral load for HIV 100 034 cp/mL, CD4: 76 cel/mcL (5%). It was performed abdominal ultrasound and denoted cysts in the liver and spleen. Abdominal-pelvic computed tomography with hepatosplenomegaly, retroperitoneal and inguinal adenopathies and free fluid in abdominal cavity. Splenectomy was performed and Burkitt's lymphoma was reported in the histopathological study.
HIV predisposes patients to any type of cancer. Intra-abdominal findings should be a warning of lymphoma suspicious and may occur from infiltration of the small intestine, solid organ and soft tissues.