Changes of respiratory system in mice exposed to PM 4.0 or TSP from exhaust gases of combustion of cashew nut shell

• Published in: Environmental toxicology and pharmacology Vol. 56; p. 1
• Main Authors: Josino, Jeanne Batista, Serra, Daniel Silveira, Gomes, Maria Diana Moreira, Araújo, Rinaldo Santos, de Oliveira, Mona Lisa Moura, Cavalcante, Francisco Sales Ávila
• Format: Journal Article
• Language: English
• Published: Netherlands 01-12-2017
• Subjects: Air Pollutants - adverse effects; Anacardium; Animals; Lung - drug effects; Lung - pathology; Male; Mice; Oxidative Stress; Particle Size; Particulate Matter - toxicity; Respiratory System - drug effects; Smoke - adverse effects; Pollution; Particulate matter; Cashew nuts shell; Combustion; Biomass; Respiratory system
• ISSN: 1872-7077

Air pollution is a topic discussed all over the world and the search for alternatives to reduce it is of great interest to many researchers. The use of alternative energy sources and biofuels seems to be the environmentally safer solution. In this work, the deleterious effects on the respiratory system of mice exposed to PM
or TSP, present in exhaust gases from the combustion of CNS were investigated, through data from respiratory system mechanics, oxidative stress, histopathology and morphometry of the parenchyma pulmonary. The results show changes in all variables of respiratory system mechanics, in oxidative stress, the histopathological analysis and lung morphometry. The results provide experimental support for epidemiological observations of association between effects on the respiratory system and exposure to PM
or TSP from CNS combustion exhaust gases, even at acute exposure. It can serve as a basis for regulation or adjustment of environmental laws that control the emissions of these gases.