Associations between Body Mass Index and Chronic Atrophic Gastritis and Intestinal Metaplasia

• Published in: The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi Vol. 70; no. 2; p. 81
• Main Authors: Kim, Nari, Youn, Chang Ho, Kim, A Sol, Ko, Hae Jin, Kim, Hyo Min, Moon, Hana, Park, Sujung
• Format: Journal Article
• Language: Korean
• Published: Korea (South) 25-08-2017
• Subjects: Adult; Alcohol Drinking; Body Mass Index; Chronic Disease; Female; Gastritis, Atrophic - complications; Gastritis, Atrophic - diagnosis; Gastroscopy; Humans; Intestines - pathology; Logistic Models; Male; Metaplasia - complications; Metaplasia - diagnosis; Middle Aged; Obesity - complications; Obesity - pathology; Odds Ratio; Risk Factors; Smoking; Surveys and Questionnaires; Body mass index; Metaplasia; Atrophic gastritis
• ISSN: 2233-6869

Chronic atrophic gastritis (AG) and intestinal metaplasia (IM) of the stomach are premalignant lesions. The present study aimed to examine the associations between obesity and these lesions.
A total of 2,997 patients, who underwent gastroscopy, participated in this study, excluding those who had been diagnosed with gastric cancer. Participants were divided into four groups based on their body mass index (BMI). The risk of AG and IM with increasing BMI was analyzed in men and women, separately.
The association between BMI and AG was not significant. After adjusting for age, smoking, alcohol, and AG, the odds ratios for IM in the overweight, obesity, and severe obesity groups were 2.25 (95% confidence interval [CI], 1.50-3.37), 2.32 (95% CI, 1.58-3.42), and 4.86 (95% CI, 2.04-11.5) in men, and 2.66 (95% CI, 1.29-5.47), 4.46 (95% CI, 2.28-8.75), and 9.57 (95% CI, 3.26-28.12) in women, compared with the normal BMI group.
Gastric IM was significantly associated with increased BMI.