The relationship between adenoids hypertrophy and secretory otitis media

To investigate the relationship between immune status of adenoids and secretory otitis media (SOM). All the 76 cases of SOM were divided into 2 groups: recurrent group (46 cases) and control group (30 cases whose occurrence was less than 3 times). The manifestation of CD45RO, CD20, PCNA and BCL-2 in...

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Bibliographic Details
Published in:	Lin chuang er bi yan hou ke za zhi = Journal of clinical otorhinolaryngology Vol. 19; no. 13; p. 588
Main Authors:	Yin, Guiru, Yue, Zhuoli, Hu, Jiangong, Zhao, Xiaoming
Format:	Journal Article
Language:	Chinese
Published:	China 01-07-2005
Subjects:	Adenoids - immunology Adenoids - pathology Antigens, CD20 - analysis Case-Control Studies Child Child, Preschool Female Humans Leukocyte Common Antigens - analysis Male Otitis Media with Effusion - immunology Otitis Media with Effusion - pathology Proliferating Cell Nuclear Antigen - analysis Proto-Oncogene Proteins c-bcl-2 - analysis Recurrence
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Summary:	To investigate the relationship between immune status of adenoids and secretory otitis media (SOM). All the 76 cases of SOM were divided into 2 groups: recurrent group (46 cases) and control group (30 cases whose occurrence was less than 3 times). The manifestation of CD45RO, CD20, PCNA and BCL-2 in adenoids was detected with ultrasensitive (TM)S-P immunohistology. The expression of CD44Ro, CD20, PCNA and BCL-2 in recurrent group was significantly higher than that in control group (P < 0.05 or P < 0.01). In adenoid tissues of recurrent SOM patients, the activities of lymphocytes and cells in hypertrophic status increase, the adenoids enlarge and local immunity enhances. Therefore, adenoidectomy for SOM patients should be carried out as early as possible.