Acquired isolated factor VII deficiency and bronchogenic carcinoma. A case report

An acquired factor VII deficiency was identified in a 63-year-old man with bronchogenic carcinoma. Initial studies indicated a normal activated partial thromboplastin time and a prolonged prothrombin time. The factor VII level was 6%. No evidence of a factor VII inhibitor or inactivator was demonstr...

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Bibliographic Details
Published in:	Tunisie Medicale Vol. 83; no. 6; p. 363
Main Authors:	Zili, Mohamed, Hammami, Sadok, Marghli, Adel, Mechmech, Lamia, Boughnim, Louisa, Abid, Salem, Brahim, N'siri, Toumi, Nour El Houda, Kilani, Tarek, Yaalaoui, Sadok
Format:	Journal Article
Language:	French
Published:	Tunisia 01-06-2005
Subjects:	Factor VII Deficiency - etiology Factor VII Deficiency - physiopathology Humans Lung Neoplasms - complications Male Middle Aged
Online Access:	Get more information
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Summary:	An acquired factor VII deficiency was identified in a 63-year-old man with bronchogenic carcinoma. Initial studies indicated a normal activated partial thromboplastin time and a prolonged prothrombin time. The factor VII level was 6%. No evidence of a factor VII inhibitor or inactivator was demonstrable. However, on account of the initial normal laboratory test of emostases, the partial correction of the prothrombin time with 50% normal plasma in vitro and the family history, the congenital deficiency in factor VII was ruled out. Whatever the mechanism involved, this factor VII deficiency was related to malignancy.
ISSN:	0041-4131