Molecular sensing by pyrene excimer signal of fluorescent DNA aptamer

Molecular sensing by pyrene excimer signal of fluorescent DNA aptamer

The pyrene excimer label (2) has been incorporated into the adjacent residue to the binding site of anti-ATP DNA aptamer. The fluorescent aptamer exhibited the specific fluorescence signal only in the presence of ATP.

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Bibliographic Details
Published in:Nucleic acids research. Supplement (2001) no. 2; p. 169
Main Authors: Ohtani, Yusuke, Yamana, Kazushige, Nakano, Hidehiko
Format: Journal Article
Language:English
Published: England 2002
Subjects:
Base Sequence
DNA - chemistry
DNA Primers
Fluorescence
Nucleic Acid Conformation
Pyrenes - chemistry
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Description
Summary:The pyrene excimer label (2) has been incorporated into the adjacent residue to the binding site of anti-ATP DNA aptamer. The fluorescent aptamer exhibited the specific fluorescence signal only in the presence of ATP.