The role of angiotensin-converting enzyme in pathogenesis of post-contusion disorders of ophthalmotonus and hemodynamics

Angiotensin converting enzyme (ACE) activity was studied in tear fluid of the contusion injured eye. We found substantial decrease of ACE activity during 1 month after trauma. Reduced ACE activity can potentiate kinin action and may contribute to the maintenance of reduced vascular tone, high capill...

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Bibliographic Details
Published in:	Voprosy meditsinskoi khimii Vol. 45; no. 3; p. 250
Main Authors:	Bendelik, E K, Kost, O A, Dotsenko, V L, Neshkova, E A, Moshetova, L K, Iarovaia, G A
Format:	Journal Article
Language:	Russian
Published:	Russia (Federation) 01-05-1999
Subjects:	Eye Injuries - enzymology Eye Injuries - physiopathology Hemodynamics Humans Peptidyl-Dipeptidase A - metabolism Tears - enzymology Wounds, Nonpenetrating - enzymology Wounds, Nonpenetrating - physiopathology
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Summary:	Angiotensin converting enzyme (ACE) activity was studied in tear fluid of the contusion injured eye. We found substantial decrease of ACE activity during 1 month after trauma. Reduced ACE activity can potentiate kinin action and may contribute to the maintenance of reduced vascular tone, high capillary permeability inducing ciliochoroidal effusion which leads to ocular hypotony. We have found decrease of ACE activity in another healthy eye.
ISSN:	0042-8809