The management of locally advanced, ulcerated breast cancer in a menopausal woman: a case report

• Published in: Annals of medicine and surgery (2012) Vol. 85; no. 10; pp. 5176 - 5178
• Main Authors: Izzo, Paolo, Izzo, Luciano, Polistena, Andrea, Sibio, Simone, Codacci-Pisanelli, Massimo, Crocetti, Daniele, Gabriele, Raimondo, De Intinis, Claudia, Izzo, Sara
• Format: Report
• Language: English
• Published: 01-10-2023
• ISSN: 2049-0801; 2049-0801
• DOI: 10.1097/MS9.0000000000001187

Introduction and importanceThis case report presents the clinical details of a 46-year-old postmenopausal woman who was diagnosed with a locally advanced, ulcerated, hormone receptor-positive, HER2-negative stage 2B lobular carcinoma of the breast. The complexity of the case necessitated a multidisciplinary, personalized approach.Case presentationThe patient, a postmenopausal woman, presented with locally advanced lobular carcinoma of the breast. The tumor was of significant size and exhibited ulceration. Given the hormone receptor-positive status of the tumor, a comprehensive treatment plan was formulated, taking into account the patient's overall health and potential tolerance to treatment. Surgical removal of the tumor was performed, followed by adjuvant therapy with aromatase inhibitors.Clinical discussionThe complexity of this case highlights the importance of a personalized and patient-centered strategy in managing breast cancer. The patient's menopausal status, tumor characteristics, and potential tolerance to treatment were crucial factors that influenced the treatment plan. The successful outcome of the treatment and the patient's ability to tolerate the therapy underscores the significance of individualized treatment planning.ConclusionThis case report emphasizes the necessity for a comprehensive and patient-centered approach to managing complex cases of breast cancer. The findings support the development of personalized therapeutic strategies aimed at improving patient outcomes and quality of life. The successful treatment of the locally advanced, ulcerated lobular carcinoma of the breast in this postmenopausal patient further highlights the importance of considering individual factors and tailoring treatment plans accordingly.