Cerebral venous sinus thrombosis in COVID 19 patients: Report of 2 cases

• Published in: Interdisciplinary neurosurgery : Advanced techniques and case management Vol. 29; p. 101599
• Main Authors: Taha, Mahmoud M, Taha, Mazen M, Al Menshawy, Hassan A, Elsharkawy, Ahmad M
• Format: Report
• Language: English
• Published: 01-09-2022
• ISSN: 2214-7519; 2214-7519
• DOI: 10.1016/j.inat.2022.101599

BackgroundInitially, novel severe acute respiratory syndrome coronavirus (SARS-CoV-2) was considered primarily a respiratory pathogen. However, with time it has behaved as a virus with the potential to cause multi-system involvement, including neurological manifestations which varies from acute to subacute onset of headache, seizures, a decrease of consciousness, and paralysis. Case descriptionTwo cases of cerebral sinus venous thrombosis in COVID-19 patients were reported, following respiratory disorders, which was triggered by the SARS-CoV-2 infection. The first patient, presented with a decrease in level of consciousness and hemiparesis, was 23 years old female having no history of previous medical co-morbidities. The latter case, 21 years old woman showed less severe presentations of COVID-19 associated with headache, vomiting and papilledema. These two cases marvellously improved with no neurological deficit with aggressive course of anticoagulation. ConclusionCVST should be suspected in COVID-19 patients presenting with headache, paralysis, aphasia or seizures. The high mortality rate of CVST in COVID-19 infection warrants a high index of suspicion from physicians, and early treatment with anticoagulation should be initiated.