Cyclic diarylheptanoids as Na super(+)-glucose cotransporter (SGLT) inhibitors from Acer nikoense

Two cyclic diarylheptanoids, acerogenins A ( 1) and B ( 2) have been isolated from the bark of Acer nikoense as inhibitors of Na super(+)-glucose cotransporter (SGLT). Acerogenins A ( 1) and B ( 2) inhibited both isoforms, SGLT1 and SGLT2. Structure-activity relationship of acerogenin derivatives on...

Full description

Bibliographic Details

Published in:	Bioorganic & medicinal chemistry letters Vol. 20; no. 3; pp. 1070 - 1074
Main Authors:	Morita, Hiroshi, Deguchi, Jun, Motegi, Yusuke, Sato, Seizo, Aoyama, Chihiro, Takeo, Jiro, Shiro, Motoo, Hirasawa, Yusuke
Format:	Journal Article
Language:	English
Published:	01-02-2010
Subjects:	Acer
Online Access:	Get full text
Tags:	Add Tag No Tags, Be the first to tag this record!