Ureaplasma diversum infection in vitro alters prostaglandin E sub(2) and prostaglandin F sub(2a) production by bovine endometrial cells without affecting cell viability

Bovine epithelial and stromal cells of the endometrium were inoculated with Ureaplasma diversum, pathogenic strain 2312, at 10 super(6) or 10 super(3) color-changing units (ccu)/ml in the presence of 1% fetal bovine serum (depleted of steroids by dextran-charcoal treatment) to assess the effect of i...

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Published in:Infection and immunity Vol. 62; no. 5; pp. 1528 - 1533
Main Authors: Kim, J J, Quinn, P A, tier, MA
Format: Journal Article
Language:English
Published: 01-01-1994
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Summary:Bovine epithelial and stromal cells of the endometrium were inoculated with Ureaplasma diversum, pathogenic strain 2312, at 10 super(6) or 10 super(3) color-changing units (ccu)/ml in the presence of 1% fetal bovine serum (depleted of steroids by dextran-charcoal treatment) to assess the effect of infection on prostaglandin biosynthesis. Alterations in prostaglandin production were not due to cell deterioration. The observations suggest that U. diversum can alter prostaglandin E sub(2) and prostaglandin F sub(2a) patterns in primary cultures of bovine endometrial cells without affecting cell viability.
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ISSN:0019-9567