Bronchial dysplasia induced by radiation in miners exposed to super(222)Rn progeny
The author's objective was to investigate whether sputum cytology can be used to monitor epithelial cell changes in groups at high risk of lung cancer from exposure to radiation. Dysplasia of bronchial cells was investigated by means of sputum cytology in a group of 434 underground miners. 100...
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| Published in: | Occupational and environmental medicine (London, England) Vol. 52; no. 2; pp. 82 - 85 |
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| Main Authors: | , , |
| Format: | Journal Article |
| Language: | English |
| Published: |
01-01-1995
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| Online Access: | Get full text |
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| Summary: | The author's objective was to investigate whether sputum cytology can be used to monitor epithelial cell changes in groups at high risk of lung cancer from exposure to radiation. Dysplasia of bronchial cells was investigated by means of sputum cytology in a group of 434 underground miners. 100 of them were not exposed, and 334 were exposed to super(222)Rn progeny at cumulative exposures < 450 working level months. The frequency of dysplasia in the exposed group was significantly higher than that in the not exposed group (P < 0.0001), and an exposure-response relation was found. This relation was different for smokers and non-smokers. |
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| Bibliography: | ObjectType-Article-2 SourceType-Scholarly Journals-1 content type line 23 ObjectType-Feature-1 |
| ISSN: | 1351-0711 |