Saponin adjuvant induction of ovalbumin-specific CD8 super(+) cytotoxic T lymphocyte responses

The ability of a saponin adjuvant, QS-21, to induce OVA-specific, class I MHC Ag-restricted CTL was investigated using different forms of soluble OVA and OVA adsorbed onto alum as immunogens. C57BL/6 mice were immunized with soluble native or denatured OVA in formulations that contained increasing q...

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Bibliographic Details

Published in:	The Journal of immunology (1950) Vol. 148; no. 8; pp. 2357 - 2362
Main Authors:	Newman, MJ, Wu, Jia-Yan, Gardner, B H, Munroe, K J, Leombruno, D, Recchia, J, Kensil, C R, Coughlin, R T
Format:	Journal Article
Language:	English
Published:	01-01-1992
Online Access:	Get full text
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