Monoclonal antibody-directed targeting of fluorescent polystyrene microspheres to Peyer's patch M cells

Monoclonal antibody-directed targeting of fluorescent polystyrene microspheres to Peyer's patch M cells

The ability to deliver particulates to Peyer's patch M cells for uptake into gut-associated lymphoid tissue was examined by administering simultaneously fluorescent green and red polystyrene microspheres into NZW rabbit intestinal loops containing Peyer's patches. The observations show tha...

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Bibliographic Details
Published in:Immunology Vol. 73; no. 3; pp. 277 - 280
Main Authors: Pappo, J, Ermak, TH, Steger, HJ
Format: Journal Article
Language:English
Published: 01-01-1990
Online Access:Get full text
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Summary:The ability to deliver particulates to Peyer's patch M cells for uptake into gut-associated lymphoid tissue was examined by administering simultaneously fluorescent green and red polystyrene microspheres into NZW rabbit intestinal loops containing Peyer's patches. The observations show that intestinal uptake into Peyer's patches can be up-regulated by targeting M-cell luminal membrane structures.
Bibliography:ObjectType-Article-2
SourceType-Scholarly Journals-1
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ISSN:0019-2805