A Kinetic Study on Drug Distribution

A Kinetic Study on Drug Distribution

To rationalize the observed time courses of furosemide distribution in arbitrarily selected tissues of rats, a phaarmacokinetic analysis based on the perfusion rate-limited model was carried out. Anatomical compartments include liver, kidneys, intestine, muscle and plasma. Required parameters were e...

Full description

Saved in:
Bibliographic Details
Published in:Chemical & pharmaceutical bulletin Vol. 36; no. 3; p. 1053
Main Authors: KITANI, MAMI, OZAKI, YUKIKO, KITAYAMA, KAZUNORI, KAKEMI, MASAWO, KOIZUMI, TAMOTSU
Format: Journal Article
Language:English
Published: Tokyo Japan Science and Technology Agency 01-03-1988
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Abstract To rationalize the observed time courses of furosemide distribution in arbitrarily selected tissues of rats, a phaarmacokinetic analysis based on the perfusion rate-limited model was carried out. Anatomical compartments include liver, kidneys, intestine, muscle and plasma. Required parameters were estimated on the basis of physiological principles for rats.
AbstractList To rationalize the observed time courses of furosemide distribution in arbitrarily selected tissues of rats, a phaarmacokinetic analysis based on the perfusion rate-limited model was carried out. Anatomical compartments include liver, kidneys, intestine, muscle and plasma. Required parameters were estimated on the basis of physiological principles for rats.
Author KITANI, MAMI
OZAKI, YUKIKO
KITAYAMA, KAZUNORI
KAKEMI, MASAWO
KOIZUMI, TAMOTSU
Author_xml – sequence: 1
  givenname: MAMI
  surname: KITANI
  fullname: KITANI, MAMI
– sequence: 2
  givenname: YUKIKO
  surname: OZAKI
  fullname: OZAKI, YUKIKO
– sequence: 3
  givenname: KAZUNORI
  surname: KITAYAMA
  fullname: KITAYAMA, KAZUNORI
– sequence: 4
  givenname: MASAWO
  surname: KAKEMI
  fullname: KAKEMI, MASAWO
– sequence: 5
  givenname: TAMOTSU
  surname: KOIZUMI
  fullname: KOIZUMI, TAMOTSU
BookMark eNrjYmDJy89LZWLgNDQ2Mdc1NTIyZmHgNDAwsNQ1MjYz5mDgKi7OMjAwMjUwN-ZkUHFU8M7MSy3JTFYILilNqVTIz1NwKSpNV3DJLC4pykwqLcnMz-NhYE1LzClO5YXS3AzKbq4hzh66BUX5haWpxSXxWfmlRXlAqXhDEzMDQ1MjcwtDY-JUAQB9vjEQ
ContentType Journal Article
Copyright Copyright Japan Science and Technology Agency 1988
Copyright_xml – notice: Copyright Japan Science and Technology Agency 1988
DBID 7TK
7TM
7U9
H94
DatabaseName Neurosciences Abstracts
Nucleic Acids Abstracts
Virology and AIDS Abstracts
AIDS and Cancer Research Abstracts
DatabaseTitle Virology and AIDS Abstracts
Nucleic Acids Abstracts
AIDS and Cancer Research Abstracts
Neurosciences Abstracts
DatabaseTitleList Virology and AIDS Abstracts
DeliveryMethod fulltext_linktorsrc
Discipline Pharmacy, Therapeutics, & Pharmacology
EISSN 1347-5223
ExternalDocumentID 3132463381
GroupedDBID ---
.55
.GJ
2WC
53G
5GY
6J9
7TK
7TM
7U9
ACGFO
ACIWK
ACPRK
ADBBV
AENEX
AFRAH
AI.
ALMA_UNASSIGNED_HOLDINGS
BAWUL
CS3
DIK
DU5
EBS
EJD
F5P
GX1
H94
HH5
JSF
JSH
KQ8
L7B
OK1
P2P
RJT
RZJ
TKC
TR2
VH1
X7M
ZGI
ID FETCH-proquest_journals_14601527813
ISSN 0009-2363
IngestDate Thu Oct 10 17:37:33 EDT 2024
IsPeerReviewed true
IsScholarly true
Issue 3
Language English
LinkModel OpenURL
MergedId FETCHMERGED-proquest_journals_14601527813
PQID 1460152781
PQPubID 1996362
ParticipantIDs proquest_journals_1460152781
PublicationCentury 1900
PublicationDate 19880301
PublicationDateYYYYMMDD 1988-03-01
PublicationDate_xml – month: 03
  year: 1988
  text: 19880301
  day: 01
PublicationDecade 1980
PublicationPlace Tokyo
PublicationPlace_xml – name: Tokyo
PublicationTitle Chemical & pharmaceutical bulletin
PublicationYear 1988
Publisher Japan Science and Technology Agency
Publisher_xml – name: Japan Science and Technology Agency
SSID ssj0025073
Score 2.688742
Snippet To rationalize the observed time courses of furosemide distribution in arbitrarily selected tissues of rats, a phaarmacokinetic analysis based on the perfusion...
SourceID proquest
SourceType Aggregation Database
StartPage 1053
Title A Kinetic Study on Drug Distribution
URI https://www.proquest.com/docview/1460152781
Volume 36
hasFullText 1
inHoldings 1
isFullTextHit
isPrint
link http://sdu.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwtV3Nb4IwFG-mp12WfWYfbmky40VJ1BaEYzMxkm5gJmbqxYjAdsJF58H_fq8UKWaJ2Q67ENJC0_B7vPd-r32vCFVjwaPNINSsRTvWqB7CPxcSQ1tYBo0MkBgrrd3ZH3bcsdm1qa0W2lXbvyINbYC1yJz9A9r5oNAA94A5XAF1uP4Kd1bn4DiKMqxDWS86qXdXm3dRZjM_3KrokeYVA4QMfH7sRbiDYm1uoZUdn7lOGkNlL3m41ZsynjZORtzhXvHhiQjgC1XCpiPXe81f4YwD_nKgIXvzVOyhZZmm2nwl7QLYc6WERKBfrQfUWZo7uqd7La1NMnUWSXVLaAeosMw43uljWRAlkztSUK7gChJltnZL9a43642en2e-Pfb3e6WVBrpNDSDiQJFLpCV2fXYdnnNycIfzw_bE5H6Y5NTP8E_RSUYQMJPInqGjKDlHtYEEZtvAvkqYWzdwDQ9U7fHtBaoynMGPU_jxMsECflyE_xI99mz_qa_t5jDLJGstKFpTHEFstsgVKifLJLpGOJjHhOh0Diy_TeeWOL9Vj5thEAdmTPXIuEGVQyPdHu6-Q8cK9Aoqf6020T0qrcPNQ_oRvwH-izZo
link.rule.ids 315,782,786
linkProvider Flying Publisher
openUrl ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=A+Kinetic+Study+on+Drug+Distribution&rft.jtitle=Chemical+%26+pharmaceutical+bulletin&rft.au=KITANI%2C+MAMI&rft.au=OZAKI%2C+YUKIKO&rft.au=KITAYAMA%2C+KAZUNORI&rft.au=KAKEMI%2C+MASAWO&rft.date=1988-03-01&rft.pub=Japan+Science+and+Technology+Agency&rft.issn=0009-2363&rft.eissn=1347-5223&rft.volume=36&rft.issue=3&rft.spage=1053&rft.externalDBID=NO_FULL_TEXT&rft.externalDocID=3132463381
thumbnail_l http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=0009-2363&client=summon
thumbnail_m http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=0009-2363&client=summon
thumbnail_s http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=0009-2363&client=summon