Evaluation of Cynomolgus Monkey Pregnane X Receptor, Primary Hepatocyte, and in Vivo Pharmacokinetic Changes in Predicting Human CYP3A4 Inductions

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Bibliographic Details
Published in:	Drug metabolism and disposition Vol. 38; no. 1; pp. 16 - 24
Main Authors:	KIM, Sean, DINCHUK, Joseph E, DULAC, Heidi A, PIZZANO, Jennifer, SINZ, Michael, ANTHONY, Monique N, ORCUTT, Tami, ZOECKLER, Mary E, SAUER, Mary B, MOSURE, Kathleen W, VUPPUGALLA, Ragini, GRACE, James E, SIMMERMACHER, Jean
Format:	Journal Article
Language:	English
Published:	Bethesda, MD American Society for Pharmacology and Experimental Therapeutics 2010
Subjects:	Biological and medical sciences Medical sciences Pharmacology. Drug treatments Human Evaluation Digestive system Enzyme Induction Isozyme Liver Cytochrome P450 Pregnane X receptor Prediction Monkey In vitro In vivo Vertebrata Mammalia Hepatocyte Animal Primary Primates Pharmacokinetics
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