Messenger Targets for Drug Action I Neurotransmitters and their receptors

Messenger Targets for Drug Action I Neurotransmitters and their receptors

This chapter deals with endogenous messenger molecules (neurotransmitters) within the human central and peripheral nervous systems (CNS, PNS), their targets, and the drugs that affect them. Since most of these messengers act on nerve cells (neurons), it is appropriate to review the anatomy and physi...

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Bibliographic Details
Published in:Medicinal Chemistry
Main Author: Weaver, Thomas Nogrady Donald F.
Format: Book Chapter
Language:English
Published: New York, NY Oxford University Press 11-08-2005
Subjects:
Biochemistry
Clinical Pharmacology and Therapeutics
Neuroscience
organizational
homeostasis
messenger
neurotransmitters
connecting
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Summary:This chapter deals with endogenous messenger molecules (neurotransmitters) within the human central and peripheral nervous systems (CNS, PNS), their targets, and the drugs that affect them. Since most of these messengers act on nerve cells (neurons), it is appropriate to review the anatomy and physiology of the nervous system and to discuss briefly the neuronal networks that can be manipulated therapeutically. Since the nervous system also influences homeostasis throughout the entire body, neurotransmitters are ideal messengers to target when designing drugs within a rational biochemical conceptual framework.
ISBN:9780195104554
0195104552
DOI:10.1093/oso/9780195104554.003.0006