Review—Micro-Fuel Cell Principal Biosensors for Monitoring Transdermal Volatile Organic Compounds in Humans

• Published in: ECS sensors plus Vol. 1; no. 4
• Main Authors: Benhaddouch, Tinsley Elizabeth, Pinzon, Sofia Kelsey, Landi, Diego Magalhaes Castro, Marcial, John, Mehta, Prateek, Romero, Karen, Rockward, Tommy, Bhansali, Shekhar, Dong, Dongmei
• Format: Journal Article
• Language: English
• Published: United Kingdom The Electrochemical Society 28-12-2022
• Subjects: Biosensors; ENGINEERING; Fuel cell; Fuel cell-based sensors; Machine Learning; Power aware computing
• ISSN: 2754-2726; 2754-2726

Abstract
Knowledge of transduction mechanisms in biosensing applications paves the way for ultrasensitive and dynamic detection in living systems. Real-world biosensing applications where ultrasensitivity and dynamic detection are paramount include monitoring the anesthetic agent concentration during surgery; the slightest variation in concentration can potentially result in a life-threatening overdose or, on the other end of the spectrum, the patient's awareness during the procedure. We review the benefits and functions of the transcutaneous biosensor device compared with other current technology and discuss the sensor's capability to accurately measure volatile anesthetic gas concentration in blood using fuel cell technology. We review fundamental concepts of fuel-cell technology for bio-sensing applications. The fuel cell sensor can also continuously monitor other volatile organic compounds making it versatile with numerous potential applications.