새로이 고안된 자바라식 천식약 흡입 보조기구(Spacer)를 이용한기관지 확장제 흡입 효과에 관한 연구

• Published in: Kosin Medical Journal (Online) pp. 6 - 10
• Main Authors: 지종현, 이창연, 홍유라, 이보영
• Format: Journal Article
• Language: Korean
• Published: 고신대학교 의과대학 학술지 01-03-2003
• Subjects: 의학일반
• ISSN: 2005-9531; 2586-7024

Object : Metered dose inhaler (MDI) is designed for administration of drugs by inhalation with a compression instrument. MDI is used widely because it is portable, more effective and has fewer side effects than oral administrations. But the proper inhalation of MDI in young children and the elderly is difficult because of their lower lung volume and ineffective compression of the device. To reduce these drawbacks, several types of spacer were invented. In this study, we evaluated the effectiveness of the newly devised closed Zavala spacer.
Method : Thirty participants were consisted of a normal group (n=14), asthmatic patients (n=13), and cases of pulmonary emphysema (n=3). FEV1 of the participants was examined before and after 2 puffs of salbutamol(200ug) inhalation with the Zavala spacer.
Results : 1. The mean improvement of FEV1 in the group of asthmatic patients was above 15% except one case 2. FEV1 was unchanged in the normal group.
Conclusion : The MDI inhalatin using the Zavala spacer would be an effctive drug delivery method for the patients who could not inhale properly. KCI Citation Count: 0