Cerebrorenal Interaction and Stroke Outcome

Cerebrorenal Interaction and Stroke Outcome

[See article vol. 25: 570-579] Chronic kidney disease (CKD) is a global health burden. CKD originally indicates a high-risk state of future hemodialysis and is now known as an independent contributor to cardiovascular disease and stroke. According to a recent systematic review and meta-analysis, str...

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Bibliographic Details
Published in:Journal of Atherosclerosis and Thrombosis Vol. 25; no. 7; pp. 566 - 567
Main Author: Masatoshi Koga
Format: Journal Article
Language:Japanese
Published: Japan Atherosclerosis Society 2018
Online Access:Get full text
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Summary:[See article vol. 25: 570-579] Chronic kidney disease (CKD) is a global health burden. CKD originally indicates a high-risk state of future hemodialysis and is now known as an independent contributor to cardiovascular disease and stroke. According to a recent systematic review and meta-analysis, stroke risk increases linearly and additively with declining glomerular filtration rate (GFR) and increasing albuminuria. In the last decade, several studies with medium sample sizes reported a significant association between CKD and stroke outcomes. However, there have been little data showing the association within a large-scale population-based setting. In the present study, Nugroho and colleagues assessed the association between admission estimated GFR (eGFR) and acute stroke outcomes, including patients with and without renal replacement therapy, using the Shiga Stroke Registry. The Shiga Stroke Registry is a multicenter, population-based, stroke registry covering all stroke cases in Shiga Prefecture (population: 1.4 million).
ISSN:1340-3478