Young-onset type 2 diabetes in South Korea: a review of the current status and unmet need
The prevalence of young-onset (diagnosis at age < 40 years) type 2 diabetes mellitus (T2DM) is increasing globally. Young-onset T2DM has a common pathophysiology of glucose dysregulation as in late-onset T2DM. However, it presents a greater association with obesity and a more rapid decline in β-c...
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Published in: | The Korean journal of internal medicine Vol. 36; no. 5; pp. 1049 - 1058 |
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Main Authors: | , , , |
Format: | Journal Article |
Language: | Korean |
Published: |
대한내과학회
30-09-2021
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Subjects: | |
Online Access: | Get full text |
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Summary: | The prevalence of young-onset (diagnosis at age < 40 years) type 2 diabetes mellitus (T2DM) is increasing globally. Young-onset T2DM has a common pathophysiology of glucose dysregulation as in late-onset T2DM. However, it presents a greater association with obesity and a more rapid decline in β-cell function than late-onset T2DM. Accumulating evidence indicates that disease progression in young-onset T2DM is rapid, resulting in early and frequent development of microvascular and macrovascular complications, as well as premature death. Improper management and low adherence to medical therapy are important issues in young-onset T2DM. This review discusses the epidemiology, disease entity, and clinical issues associated with young-onset T2DM. We also present the prevalence and clinical characteristics of patients with young-onset T2DM in South Korea. |
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Bibliography: | The Korean Association Of Internal Medicine |
ISSN: | 1226-3303 2005-6648 |