Sinusoidal fitting using exact linearization applied to bioimpedancimetric measurements

• Published in: Proceedings of the 20th Annual International Conference of the IEEE Engineering in Medicine and Biology Society. Vol.20 Biomedical Engineering Towards the Year 2000 and Beyond (Cat. No.98CH36286) Vol. 3; pp. 1665 - 1667 vol.3
• Main Authors: Madrid, R.E., Spinelli, E.M., Felice, C.J.
• Format: Conference Proceeding
• Language: English
• Published: IEEE 1998
• Subjects: Additive white noise; Bioimpedance; Dielectric measurements; Electrodes; Equations; Frequency; Impedance measurement; Instruments; Microorganisms; Parameter estimation
• ISBN: 0780351649; 9780780351646
• ISSN: 1094-687X; 1558-4615
• DOI: 10.1109/IEMBS.1998.747228

Microbial growth can be continuously followed up by measuring the interface impedance Z/sub i/ of two electrodes immersed in a culture medium. A new method based on sinusoidal fitting is used to reduce measurement errors. It applies an exact linearization with which it is possible to obtain a linear relationship of the parameters to be estimated. This permits the application of the least squares procedure, producing pure sinusoidal waves, which greatly reduce the error in the determination of the interface impedance amplitude and phase components.