Polarizing and maintenance activities in two polydactylous mutants of the fowl: diplopodia1 and talpid2

In two polydactylous mutants, talpid 2 and diplopodia 1 , polarizing activity appears to be present only in the normal location in the posterior corner of the limb-bud. There is, thus, a preaxial extension of maintenance activity without an accompanying extension of demonstrable polarizing activity....

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Bibliographic Details
Published in:Development (Cambridge) Vol. 31; no. 3; p. 735
Main Authors: Jeffrey A. MacCabe, Ursula K. Abbott
Format: Journal Article
Language:English
Published: Cambridge University Press for The Company of Biologists Limited 01-06-1974
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Summary:In two polydactylous mutants, talpid 2 and diplopodia 1 , polarizing activity appears to be present only in the normal location in the posterior corner of the limb-bud. There is, thus, a preaxial extension of maintenance activity without an accompanying extension of demonstrable polarizing activity. Experiments involving apex exchanges between normal and talpid 2 wing-buds suggest that the movement of ‘maintenance factor’ per se from preaxial talpid 2 limb tissue into a normal apex does not occur.
ISSN:0950-1991
1477-9129