Identification of Secondary Metabolites from the Mangrove-Endophyte ILasiodiplodia iranensis/I F0619 by UPLC-ESI-MS/MS

• Published in: Metabolites Vol. 13; no. 8
• Main Authors: Delgado Gómez, Lizbeth M, Torres-Mendoza, Daniel, Hernández-Torres, Kathleen, Ortega, Humberto E, Cubilla-Rios, Luis
• Format: Journal Article
• Language: English
• Published: MDPI AG 01-08-2023
• Subjects: Ascomycota; Chemical properties; Diseases and pests; Fungi; Fungi, Phytopathogenic; Health aspects; Identification and classification; Mangrove plants; Metabolites; Panama
• ISSN: 2218-1989; 2218-1989
• DOI: 10.3390/metabo13080912

Lasiodiplodia is a widely distributed fungal genus, frequently found in tropical and subtropical regions where it can cause disease in important crops. It represents a promising source of active secondary metabolites with uses in chemical, pharmaceutical, and agrochemical processes. In this study, the strain Lasiodiplodia iranensis F0619 was isolated from the mangrove Avicennia ger-minans, collected from Sarigua National Park in the Republic of Panama. Fractions of crude extract were analyzed by UPLC-ESI-MS/MS, and five compounds, previously reported from Lasiodiplodia genus were identified, including 11,12-didehydro-7-iso-jasmonic acid (1), 4,5-didehydro-7-iso-jasmonic acid (2), cyclo-(L-Leu-L-Pro) (3), jasmonate-threonine (4), and abscisic acid (5). We describe and analyze their MS/MS fragmentation patterns to confirm the compounds ‘chemical structures.