On the application of knoevenagel condensation for the synthesis of benzylidene benzothiazine compounds and structural study

On the application of knoevenagel condensation for the synthesis of benzylidene benzothiazine compounds and structural study

The synthesis and physico-chemical properties of new 6-acetylamino or 6-benzoyl-amino 2-benzylidene-4-methyl-4H-benzo[1,4]thiazin-3-ones and 6-benzoylamino or 6-nitro 2-benzylidene-4H-benzo[1,4]thiazin-3-ones are described. These benzylidene benzothiazine compounds were prepared by the Knoevenagel c...

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Bibliographic Details
Published in:Química nova Vol. 29; no. 5; pp. 1106 - 1109
Main Authors: Souza Ana Maria Alves de, Guarda Vera Lucia de Miranda, Leite Lúcia Fernanda Cavalcanti da Costa, Barbosa Filho José Maria, Lima Maria do Carmo Alves de, Galdino Suely Lins, Pitta Ivan da Rocha
Format: Journal Article
Language:English
Published: Sociedade Brasileira de Química 01-01-2006
Subjects:
AM1 conformational and configurational analysis
benzothiazines
benzylidene benzothiazines
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Summary:The synthesis and physico-chemical properties of new 6-acetylamino or 6-benzoyl-amino 2-benzylidene-4-methyl-4H-benzo[1,4]thiazin-3-ones and 6-benzoylamino or 6-nitro 2-benzylidene-4H-benzo[1,4]thiazin-3-ones are described. These benzylidene benzothiazine compounds were prepared by the Knoevenagel condensation with benzaldehydes. The configurations and conformations of benzylidene benzothiazine derivatives were optimised using the semi-empirical method AM1.
ISSN:0100-4042
1678-7064