BIOCENOSIS VAGINA AT THE VERY EARLY PRETERM LABOR

• Published in: Medicinskij vestnik Ûga Rossii no. 4; pp. 90 - 94
• Main Authors: V. E. Radzinskiy, A. A. Orazmuradov, V. F. Arakelyan
• Format: Journal Article
• Language: English
• Published: State Budget Educational Institute of Higher Professional Education, Rostov State Medical University, Ministry Health of Russian Federation 01-12-2014
• Subjects: vaginal biocenosis; very early preterm delivery
• ISSN: 2219-8075; 2618-7876
• DOI: 10.21886/2219-8075-2014-4-90-94

Purpose: consideration of the timing of initiation of antibiotic therapy in the identification of pathogenic infekt, schemes and duration of treatment, the appropriateness of antibiotic therapy at very early preterm delivery.Materials and methods: a total of 111 pregnant women in terms of 22-25 weeks of gestation with the threat of premature birth. Depending on the condition of the vagina biocenosis are divided into three groups: normotsenoz (n = 35), bacterial vaginosis (BV) (n = 40) vaginitis (n = 36). All pregnant women were examined in accordance with the order number 572n Health Ministry. A comprehensive microbiological research. All pregnant at admission was conducted therapy aimed at prolongation of pregnancy leads to: medical protective regime, diet agravatsiey protein tocolytic therapy, normalization of biocenosis of the genital tract.Results: in pregnant women with threatened preterm birth at 22-25 weeks of gestation duration of pregnancy depend in particular on the state of the biocenosis of the genital tract. Adverse predictors of premature birth is a combination of BV with persistence of Ureaplasma urealyticum, Mycoplasma hominis and Mycoplasma genitalium in the cervical canal pregnant. Enabling correction of biocenosis of the genital tract in the complex therapy aimed at prolongation of pregnancy in women with BV and vaginitis, does not lead to a significant reduction in the incidence of preterm birth.Summary: conducted correction of biocenosis of the genital tract, including antibacterial therapy, in terms of 22-25 weeks of gestation is not able to reduce the rate of preterm birth, as the process of infection of the membranes is already running. The development of preterm labor depends on the area of infection and membranes.