Experience of treatment of hairy cell leukemia with new drug Vero-cladribine

Experience of treatment of hairy cell leukemia with new drug Vero-cladribine

Between July 2005and October 2006, eight patients (pts) with hairy cell leukaemia were treated with Vero- cladribine at N.N. Blokhin Cancer Research Center. All pts achieved complete remission (CR). Duration of CR ranges from 1+ to 12+ months in 7 cases. There were no serious adverse events during t...

Full description

Saved in:
Bibliographic Details
Published in:Onkogematologii͡a no. 1; pp. 31 - 37
Main Authors: Yu. E. Ryabukhina, A. D. Shirin, O. L. Timofeeva, N. N. Tupitsyn, M. A. Frenkel, N. A. Kupryshina, M. A. Volkova
Format: Journal Article
Language:Russian
Published: ABV-press 01-11-2022
Subjects:
2-chlorodeoxyadenosine
cladribine
hairy cell leukaemia
treatment
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Between July 2005and October 2006, eight patients (pts) with hairy cell leukaemia were treated with Vero- cladribine at N.N. Blokhin Cancer Research Center. All pts achieved complete remission (CR). Duration of CR ranges from 1+ to 12+ months in 7 cases. There were no serious adverse events during the treatment and follow-up periods (1-12 months). Vero- cladribine was well tolerated. Anemia (grade IV) was seen in 1 patient and thrombocytopenia (grade I) was seen in another 1 patient. No one patient has febrile neutropenia or infectious complication.
ISSN:1818-8346
2413-4023
DOI:10.17650/1818-8346-2007-0-1-31-37