Measles vaccination in children with neurological disorders

• Published in: Zhurnal infektologii Vol. 4; no. 2; pp. 51 - 55
• Main Authors: S. P. Kaplina, S. M. Kharit, O. V. Goleva, E. I. Aleksandrova
• Format: Journal Article
• Language: Russian
• Published: Journal Infectology 01-09-2014
• Subjects: antibody formation; children with damage to the nervous system; vaccination of measles
• ISSN: 2072-6732
• DOI: 10.22625/2072-6732-2012-4-2-51-55

The data on the current vaccination process and specific antibody in 212 children with pathology of nervous systems in age from 1 year to 6 years old, vaccinated against measles. The comparison group consisted of 36 children without neurological disease. 86 children (40,6%) were vaccinated measles – mumps vaccine, and 126 children (59,4%) only measles vaccine. Post-vaccination period in 77,8% immunized against measles, was uneventful, layering intercurrent infections was noted in 22,2% of vaccine’s, and demonstrated the development of viral respiratory infections, bronchitis, otitis media and exacerbation of underlying disease. It is shown that the level of specific antibody to measles in children with pathology of nervous systems at 30 days after vaccination was 5,04±0,16 log 2, which did not differ from the comparison group (5,88±0,31 log 2). No significant differences in the level of antibody in a smooth and complicated course of vaccination period were found. Immunization of children with disorders of the nervous system of live vaccines is quite effective and leads to the formation of protective antibody titers in all vaccinated.