Abstract P369: Ambulatory Blood Pressure Monitoring Profile as a Useful Tool - Assessment of an Adult Population in the Real World

• Published in: Hypertension (Dallas, Tex. 1979) Vol. 70; no. suppl_1
• Main Authors: Prado, Yasmin S, Rodrigues, Livia F, Lopes, Patricia d, Rocha, Ligia d, Lucci, Maria A, dos Santos, Mariella P, Almeida, Paulo E, Costa, Lílian S
• Format: Journal Article
• Language: English
• Published: 01-09-2017
• ISSN: 0194-911X; 1524-4563
• DOI: 10.1161/hyp.70.suppl_1.p369

Abstract only
Introduction:
The pattern of therapeutic and diagnostic control of arterial hypertension (AH) has been better evaluated with the use of Ambulatory Blood Pressure Monitoring (ABPM) in clinical practice.
Objective:
The purpose of the study was to evaluate the blood pressure (BP) profile through data obtained in an adult population (18-59 years), and to further determine the differences of BP readings between users (G1) and non-users (G2) antihypertensive drugs.
Method:
In a cohort of 2222 non-elderly subjects, both genders, mean 43 years (56.8% female), referred for ABPM from an outpatient set-up, we studied 24-hour ABPM patterns.
Results:
Of 2222 adults, 1324 (59.6%) were off antihypertensive medications (G2) and of the remaining, 751 (33.8%) used one or two drugs and 6.6% used three or more drugs. Analysis of variance was applied for a comparative study of therapeutic control between groups, with a significance level of
p
less than 0.05. From the G2, 898 subjects (67,8%) had 24-hour BP within normal limits (119x71mmHg) and, 426 (32,2%) had an elevated mean 24-hour BP (139x87mmHg). Of the G1, subjects in monotherapy, double or triple or more antihypertensive therapies presented satisfactory control in 68% (118x71mmHg), 72% (117x70mmHg) and 66% (119x71mmHg) respectively, with no statistically significant difference between groups. The mean nocturnal drop expressed in percentage for the SBP and DBP in G2, was 11.9±2.03 and 18.4±7.19 in normotensive subjects, and 11.1±4.05 and 16.8±8.02 in hypertensive subjects, with no significant difference between different gender groups (p=0.6). Irrespective of normal nocturnal drop values in G1, we observed a significant attenuation in the subgroup using three or more drugs (percentage of 10.1±6.02 and 14.8±6.13) compared to those with monotherapy or double therapy (11.0±4 and 16.6±4.08), both with similar pattern in their dipping profile.
Conclusion:
The percentage diagnosis of AH by ABPM (32%) is similar to the reported papers in the literature. The pattern of nocturnal drop may help the identification of target organ damages and help in determination of therapeutic adjustments, corroborating literature data, which emphasize the use of ABPM study in the diagnostic and therapeutic evaluation.