Abstract 15885: A Masquerading Early Beat Induces Ventricular Fibrillation

• Published in: Circulation (New York, N.Y.) Vol. 148; no. Suppl_1
• Main Authors: Kloo, Juergen H, Laslett, David B, Gunchenko, Melissa, Cronin, Edmond
• Format: Journal Article
• Language: English
• Published: 07-11-2023
• ISSN: 0009-7322; 1524-4539
• DOI: 10.1161/circ.148.suppl_1.15885

Abstract only
Clinical Case:
A 51 year old male with a history of hypertension, G6PD deficiency, thrombotic thrombocytopenic purpura, prior stroke, and morbid obesity presented with resuscitated out of hospital VF arrest. Electrolytes and ECG were normal. During his admission, the patient had two VF events that were induced by what appeared to be a short coupled right bundle branch block (RBBB) morphology PVC. He was brought to the electrophysiology lab for PVC ablation and ICD implantation. Baseline rhythm was sinus with what appeared to be both RBBB morphology PVCs and junctional extrasystoles. With both extrasystoles, the His potential preceded the QRS by 50 ms, and atrial activation in the His catheter and coronary sinus catheter was also earlier than the QRS. Activation mapping of the right bundle showed later activation than the His potential. This was all consistent with junctional premature complexes (JPC) with frequent RBBB aberrancy rather than fascicular PVCs. Slow pathway modification was performed to attempt to ablate the JPCs. After multiple ablations along the tricuspid annulus and back to the coronary sinus os that triggered slow junctional beats, the patient’s JPC burden was significantly reduced. An ICD was also implanted. The patient was discharged on flecainide. At 4 month follow up he had not had recurrence.
Discussion:
Early coupled PVCs are a well-known cause of ventricular fibrillation, but JPCs inducing VF have not been described previously. Placement of a coronary sinus and His catheter helped identify early that this was not simply a fascicular PVC. This case demonstrates the importance of keeping a broad differential diagnosis when starting any EP study. Ablating the slow pathway area can be effective to treat JPCs while preserving native AV conduction as demonstrated in this case.