双侧内关激光多普勒血流量侧性及其Coherence分析:一种无创评价不同年龄人群微循环状态的潜在方法

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Bibliographic Details
Published in:世界针灸杂志:英文版 Vol. 27; no. 1; pp. 47 - 52
Main Author: 王广军 田宇瑛 贾术永 王泽 张维波
Format: Journal Article
Language:English
Published: 2017
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Bibliography:WANG Guang-jun , TIAN Yu-ying , JIA Shu-yong , WANG Ze , ZHANG Wei-bo ( Institute of Acupuncture and Moxibustion, China Academy of Chinese Medical Sciences, Beijing, 100700, China)
11-2892/R
acupoint; acupoint laterality; laser doppler blood flowmetry; Neiguan (内关 PC 6); coherence analysis
Objective To investigate lateralization and Coherence analysis of blood perfusion in bilateral Neiguan (内关 PC 6) in different ages. Methods Healthy volunteers (n=30) were placed in a temperature-controlled room as a resting state for 40 min. Then the blood perfusion of bilateral PC 6 were carried out using PeriFlux System 5000 for 25 minutes. Mean blood flux of every 5 minutes was calculated. Then the participants were divided into groups of young (n=18) and the old (n=12) as the boundary of 40 years, the asymmetry index and coherence value of bilateral PC 6 were analyzed in different group. Results The mean blood flow of the right PC 6 was significantly higher than the left PC 6 in three different epochs, the mean blood flow of right PC 6 vs left PC 6 is 9.74±3.36 vs 6.73±2.22 (t=5.9, P〈0.001), 9.83±3.63 vs 6.99±2.37 (t=5.11, P〈0.001) and 9.69±3.40 vs 6.77±2.32 (t=5.99, P〈0.001), respectively. Although the asymmetry index is higher in old group than in young group, there is no statistically significant age-related differences. Coherence analysis suggest that there is significant difference in frequency value corresponding to peak crest between young and old group. Conclusion The blood perfusion in right PC 6 is higher than left PC 6. Coherence analysis of laser Doppler flowmetry signals in bilateral PC 6 might provide a potential non-invasive method to assess microcirculatory changes in different ages.
ISSN:1003-5257