Post-caesarean section outcomes of obstetric patients with valvular heart disease at Charlotte Maxeke Johannesburg Academic Hospital, South Africa

• Published in: South African journal of obstetrics and gynaecology (1999) Vol. 28; no. 2; pp. 1 - 5
• Main Authors: Mfeka, Z, Nkuna, A, Chakane, P Motshabi
• Format: Journal Article
• Language: English
• Published: South African Medical Association NPC 01-06-2023; South African Medical Association
• Subjects: Obstetrics & Gynecology
• ISSN: 0038-2329; 2305-8862; 2078-5135
• DOI: 10.7196/SAJOG.2023.v29i1.2110

\r\nBackground\r\nValvular heart disease presents a unique set of conditions during pregnancy and delivery, with the potential for adverse outcomes increased by prior interventions and anticoagulation.\r\n\r\nObjectives\r\nTo describe the profile and outcomes of obstetric patients with valvular heart disease who delivered via caesarean section at Charlotte Maxeke Johannesburg Academic Hospital, South Africa.\r\n\r\nMethods\r\nA 5-year retrospective descriptive cross-sectional study was performed. All patients with valvular heart disease who underwent caesarean section, irrespective of age, were included. Exclusion criteria were absence of important clinical data relevant to the study and outcomes data. All records of patients who delivered by caesarean section and were booked in the obstetric cardiac unit were reviewed. Data for those who had valvular heart disease were separated from non-valvular heart disease data. A total of 69 patients were included in the analysis. Univariate logistic regression analysis was done to assess the predictors of maternal and fetal outcomes.\r\n\r\nResults\r\nThe mean (standard deviation) age of the patients in the study was 30.1 (5.6) years, 82.6% were gravida 1 - 3 and 89.8% para 0 - 2, and the majority (56.5%) had an elective caesarean section. General anaesthesia was the most common mode used, and most of the patients had fixed-interval analgesia postoperatively. Approximately two-fifths of the patients (n=28; 40.6%) were on anticoagulants. A significantly higher percentage of those who were on anticoagulants had complications (n=12/28; 42.9%) compared with those who were not on anticoagulants (n=3/41; 7.3%) (p4), and most pregnancies continued to term or early term (median (interquartile range) 37 (36 - 38) weeks). Some patients experienced adverse outcomes, mainly related to bleeding and arrhythmias, but none died. There was one early neonatal death. These patients need a structured multidisciplinary team care plan.