The Synergistic Effect of Cisplatin and Interferon β on Human Lung Adenocarcinoma Cell Line (A549)

[...]induction of apoptosis to cancer cell line may be an important mechanism and promising results of anti- tumor. [...]reduce the transcription factor which rises the sensitivity of cancer cells to the necrosis through the exploit of chemotherapeutic drugs [11]. [...]tow highest concentrations app...

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Bibliographic Details
Published in:	Journal of pharmaceutical sciences and research Vol. 10; no. 8; pp. 1939 - 1942
Main Authors:	Obied, Hamid Naji, Enayah, Sabah H, Ghaleb, Rana A, Obaid, Rasha F
Format:	Journal Article
Language:	English
Published:	Cuddalore Journal of Pharmaceutical Sciences and Research 01-08-2018
Subjects:	Apoptosis Breast cancer Cancer therapies Cell cycle Cervical cancer Chemotherapy Drug dosages Interferon Liver cancer Lung cancer Metastasis Transcription factors Tumors
Online Access:	Get full text
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Summary:	[...]induction of apoptosis to cancer cell line may be an important mechanism and promising results of anti- tumor. [...]reduce the transcription factor which rises the sensitivity of cancer cells to the necrosis through the exploit of chemotherapeutic drugs [11]. [...]tow highest concentrations applied showed low number of the cells at 24(37.04+62.96), 48(8.439+1.84) and 72h (22.63+77.37) figure (3). [...]INF- ß would synergistically, even with small dose, enhanced cell growth inhibitory impact of Cis on human lung cells that treated in combination of INF- ß and Cis for 48 and 72h.
ISSN:	0975-1459