Ciliary changes with abscence of dynein arms in Kartagener's syndrome

Ciliary changes with abscence of dynein arms in Kartagener's syndrome

A 33 years-old female with a diagnosis of Kartagener's syndrome was studied. She had a clinical history of chronic sinusitis with nasal obstruction and rhinorrea, and a chronic cough with mucopurulent sputum. A paranasal sinus CT showed hypertrophyc mucosa. A thoracic CT showed a situs inversus...

Full description

Saved in:
Bibliographic Details
Published in:Acta otorrinolaringológica española Vol. 55; no. 3; p. 145
Main Authors: Melgarejo Moreno, P, Galindo Ortego, X, Marqués Amat, L, Torres Cortada, G, Hellin Meseger, D, García González, B
Format: Journal Article
Language:English
Spanish
Published: Spain 01-03-2004
Subjects:
Adult
Dyneins - ultrastructure
Female
Humans
Kartagener Syndrome - pathology
Online Access:Get more information
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:A 33 years-old female with a diagnosis of Kartagener's syndrome was studied. She had a clinical history of chronic sinusitis with nasal obstruction and rhinorrea, and a chronic cough with mucopurulent sputum. A paranasal sinus CT showed hypertrophyc mucosa. A thoracic CT showed a situs inversus and chronic bronchitis with bronchiectasis. The saccharin test lasted 55 minutes. The electron microscopy study showed in a a cross-sectional axoneme a total absence of the outer and inner arm of the 9th outer doublet in over a 100 cilias studied. No others ultrastructure anormalities were observed.
ISSN:0001-6519
DOI:10.1016/s0001-6519(04)78498-8