Endocrine function of the thymus and ionizing radiation

It is shown that external as well as incorporated radiation inhibit the endocrine function of the thymus in the result of the direct and indirect effects. Postradiation deficiency of thymic hormones plays a significant role in pathogenesis of functional disorders in the immunity system. Immunocorrec...

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Bibliographic Details
Published in:	Radiat͡s︡ionnai͡a︡ biologii͡a︡, radioėkologii͡a Vol. 35; no. 3; p. 391
Main Authors:	Grinevich, Iu A, Martynenko, S V
Format:	Journal Article
Language:	Russian
Published:	Russia (Federation) 01-05-1995
Subjects:	Adult Animals Child Humans Immune System - radiation effects Immune System Diseases - etiology Immune System Diseases - therapy Male Mice Middle Aged Power Plants Radiation Dosage Radiation Injuries Radiation Injuries, Experimental Radiation, Ionizing Radioactive Hazard Release Rats Thymus Extracts - therapeutic use Thymus Gland - immunology Thymus Gland - physiology Thymus Gland - radiation effects Thymus Hormones - blood Thymus Hormones - physiology Ukraine Ukraine
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Summary:	It is shown that external as well as incorporated radiation inhibit the endocrine function of the thymus in the result of the direct and indirect effects. Postradiation deficiency of thymic hormones plays a significant role in pathogenesis of functional disorders in the immunity system. Immunocorrection with thymic agents is the most effective method when the mechanism of inhibition of thymic hormonal function are taken into account.
ISSN:	0869-8031