CHARACTERISATION AND POTENT BACTERICIDAL EFFECT OF COBALT DOPED TITANIUM DIOXIDE NANOFIBRES

• Published in: Ceramics international Vol. 39; no. 3; pp. 3189 - 3193
• Main Authors: Amna, T, Hassan, M S, Pandurangan, M, Khil, M-S, Lee, H-K, Hwang, I H
• Format: Journal Article
• Language: English
• Published: 01-01-2013
• Subjects: Bacteria; Cobalt; Electrospinning; Nanocomposites; Nanomaterials; Nanostructure; Salmonella typhimurium; Titanium dioxide; Transmission electron microscopy
• ISSN: 0272-8842

The fabrication and characterisation of novel cobalt-doped titanium dioxide nanofibres and their antibacterial properties are reported. The Co-doped TiO2 nanofibres were prepared by electrospinning and the physicochemical characterisation of the electrospun nanofibres was carried out by XRD, SEM/EDX and TEM. The antibacterial activity was tested against two common foodborne pathogenic bacteria staplylococcus aureus (Gram-positive) and salmonella typhimurium (Gram-negative). Bactericidal effects were determined using the minimum inhibitory concentration (MIC) method and TEM analysis respectively. The results suggested that the Co-doped TiO2 nanofibres inhibited the growth of the selected strains. TEM demonstrated that the exposure of bacteria to the Co-doped TiO2 nanofibres led to disruption of cell membranes and respective membrane enzymes which caused bacteria to eventually die. The observed antimicrobial action of Co-doped TiO2 when compared to virgin TiO2 nanofibres was due to the synergistic impact of cobalt oxide and TiO2.