Patent Ductus Arterious and the Immature Brain: Is Early Intervention Protective?

Patent Ductus Arterious and the Immature Brain: Is Early Intervention Protective?

Patent ductus arteriosus (PDA), in which the ductus arteriosus fails to close after birth, is a common congenital heart defect in premature infants. Lemmers et al present a retrospective comparison of cerebral oxygenation, as measured by near infrared spectroscopy, and MRI-assessed regional brain vo...

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Bibliographic Details
Published in:Pediatrics (Evanston) Vol. 137; no. 4; p. 1
Main Authors: Tsang, Rocky, Shekerdemian, Lara S
Format: Journal Article
Language:English
Published: Evanston American Academy of Pediatrics 01-04-2016
Subjects:
Brain
Cardiovascular disease
Congenital diseases
Early intervention
Oxygen
Pediatrics
Premature birth
Online Access:Get full text
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Summary:Patent ductus arteriosus (PDA), in which the ductus arteriosus fails to close after birth, is a common congenital heart defect in premature infants. Lemmers et al present a retrospective comparison of cerebral oxygenation, as measured by near infrared spectroscopy, and MRI-assessed regional brain volume and myelination in 3 groups of premature infants. Their findings confirm that a hemodynamically significant PDA is associated with reduced regional cerebral oxygenation saturation (rSco...) and that the infants who needed surgery had significantly lower rSco... before ductal closure than those who did not. (ProQuest: ... denotes formulae/symbols omitted.)
Bibliography:ObjectType-Article-1
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ISSN:0031-4005
1098-4275