Impact of the examined number of lymph nodes at N1 station on the prognosis of patients with pT1-3N0M0 non-small cell lung cancer

• Published in: Zhōnghuá zhŏngliú zázhì Vol. 44; no. 2; p. 155
• Main Authors: Wang, G X, Li, T, Xu, S B, Wang, J, Xiong, R, Xu, M Q, Xie, M R
• Format: Journal Article
• Language: Chinese
• Published: China 23-02-2022
• Subjects: Carcinoma, Non-Small-Cell Lung - drug therapy; Carcinoma, Non-Small-Cell Lung - surgery; Humans; Lung Neoplasms - drug therapy; Lung Neoplasms - surgery; Lymph Nodes - pathology; Lymph Nodes - surgery; Lymphatic Metastasis - pathology; Neoplasm Staging; Prognosis; Retrospective Studies; Carcinoma, non-small cell lung; Clinicopathological characteristics; Prognosis; Lymph node
• ISSN: 0253-3766
• DOI: 10.3760/cma.j.cn112152-20200331-00284

To investigate the relationship between the examined number of lymph nodes at the N1 station and the clinicopathological characteristics and prognosis of patients with pT1-3N0M0 non-small cell lung cancer (NSCLC).
A total of 337 patients with pT1-3N0M0 NSCLC who underwent radical lung cancer surgery at the Provincial Hospital Affiliated to Anhui Medical University from January 2013 to March 2015 were selected. The receiver operating characteristic (ROC) curve analysis was used to determine the optimal cut-off value for predicting 5-year survival in pT1-3N0M0 NSCLC patients by the examined number of lymph nodes at the N1 station. The relationships between the examined number of lymph nodes at the N1 station and the clinicopathological characteristics and prognosis of patients with pT1-3N0M0 NSCLC were analyzed according to the optimal cut-off group.
A total of 1 321 lymph nodes at N1 station were examined in 337 patients, with a mean of 3.9 nodes per patient. The median survival time was 42.0 months, with 1-,